Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in different populations.
نویسندگان
چکیده
منابع مشابه
Association between two single base polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease
AIM The present study evaluated the association between G241R and K469E polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease in Iranian population. BACKGROUND Inflammatory bowel disease including ulcerative colitis and Crohn's disease, is a chronic idiopathic inflammatory disease of the gastrointestinal tract. There are two single base polymorphisms of interc...
متن کاملINFLAMMATORY BOWEL DISEASE Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population
Background and aims: The genetic contribution to inflammatory bowel disease (IBD) is under investigation. Recent evidence indicates a significant linkage between a locus on chromosome 19p13 and IBD. We investigated the association between an intercellular adhesion molecule 1 gene (ICAM-1) polymorphism located on chromosome 19p13 and IBD in a Japanese population. Methods: We compared 207 Japanes...
متن کاملAssociation between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population.
BACKGROUND AND AIMS The genetic contribution to inflammatory bowel disease (IBD) is under investigation. Recent evidence indicates a significant linkage between a locus on chromosome 19p13 and IBD. We investigated the association between an intercellular adhesion molecule 1 gene (ICAM-1) polymorphism located on chromosome 19p13 and IBD in a Japanese population. METHODS We compared 207 Japanes...
متن کاملIntercellular adhesion molecule 1 gene polymorphisms in inflammatory bowel disease.
Intercellular adhesion molecule (ICAM)-1 is a single-chain cell surface glycoprotein that plays an important role in the recruitment of leukocytes at sites of inflammation and is up-regulated in intestinal mucosa of inflammatory bowel disease (IBD). ICAM-1 gene lies on chromosome 19p13, implicated in determining susceptibility to IBD. The human ICAM-1 gene contains two polymorphic sites in codo...
متن کاملIntercellular Adhesion Molecule-1 K469E Polymorphism and Risk of Coronary Artery Disease: A Meta-Analysis
BACKGROUND Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism has been implicated in susceptibility to coronary artery disease (CAD). Several studies investigated the association of this polymorphism with CAD in different populations but the results were contradictory. A meta-analysis was conducted to assess the association between ICAM-1 K469E polymorphism and CAD susceptibility. ...
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ورودعنوان ژورنال:
- Gut
دوره 52 8 شماره
صفحات -
تاریخ انتشار 2003